Synthesis of pyrazolines by a site isolated resin-bound reagents methodology.
نویسندگان
چکیده
The elaboration of biologically important 3,4-substituted pyrazolines was achieved by an organocatalysed aza-Michael/transimination domino sequence between hydrazones and enones making use of a mixture of heterogeneous resin-bound acid/base reagents. This methodology nicely illustrates the site isolation concept of supported reagents allowing the simultaneous use of otherwise destructive reactive functionalities.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 8 14 شماره
صفحات -
تاریخ انتشار 2010